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pentobarbital will lower the extent or impact of isavuconazonium sulfate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.pentobarbital will reduce the extent or outcome of alosetron by influencing hepatic enzyme CYP2C9/10 metabolism. Slight/Significance Unknown.pentobarbital will lower the level or impact of glecaprevir/pi